PIPA5114343

SPATA13 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5114343-Each-of-1 In Stock ₹ 46,502.50

PIPA5114343 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

SPATA13

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Spata13

Gene Alias

adenomatous polyposis coli stimulated exchange factor 2; APC-stimulated guanine nucleotide exchange factor 2; ARHGEF29; ASEF2; C79050; ESTM11; mFLJ00298; Spata13; spermatogenesis associated 13; spermatogenesis-associated protein 13; spt13; X83327

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

219140, 221178, 305938

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q5DU57, Q96N96

Gene Symbols

Spata13

Immunogen

Recombinant protein within Human SPATA13 aa 423-572

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases
  • Regulates cell migration and adhesion assembly and disassembly through a RAC1, PI3K, RHOA and AKT1-dependent mechanism
  • Increases both RAC1 and CDC42 activity, but decreases the amount of active RHOA
  • Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells
  • Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression
  • [UniProt]