PIPA5114479

UCP1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5114479-Each-of-1 In Stock ₹ 46,502.50

PIPA5114479 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

UCP1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Ucp1

Gene Alias

AI385626; HGNC:12517; mitochondrial brown fat uncoupling protein 1; SLC25A7; solute carrier family 25 member 7; Thermogenin; Ucp; UCP 1; Ucp1; Ucpa; uncoupling protein; uncoupling protein 1; uncoupling protein 1 (mitochondrial, proton carrier); uncoupling protein 1, mitochondrial; uncoupling protein, mitochondrial; Uncp; unnamed protein product

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

22227, 24860, 7350

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

P04633, P12242, P25874

Gene Symbols

Ucp1

Immunogen

UCP1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human UCP1 (GenBank accession. The immunogen is located within the last 50 amino acids of UCP1.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Positive controls that may be used include: Human Brain Tissue Lysate, Human Liver Tissue Slide Mitochondrial uncoupling proteins are members of the family of mitochondrial anion carrier proteins
  • UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak
  • UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane
  • They also reduce the mitochondrial membrane potential in mammalian cells
  • Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known
  • UCPs contain the three homologous protein domains of MACPs
  • This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat.