PIPA5114629

Phospho-MPZL1 (Tyr263) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5114629-Each-of-1 In Stock ₹ 46,502.50

PIPA5114629 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

Phospho-MPZL1 (Tyr263)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Mpzl1

Gene Alias

1110007A10Rik; FLJ21047; immunoglobulin family transmembrane protein; Mpzl1; MPZL1b; myelin protein zero like 1; myelin protein zero-like 1; myelin protein zero-like protein 1; protein zero related; protein zero-related; Pzr; PZR1b; PZRa; PZRb; UNQ849/PRO1787

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

360871, 68481, 9019

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.

O95297, Q3TEW6, Q6AYT8

Gene Symbols

Mpzl1

Immunogen

A synthesized peptide derived from human MPZL1(Accession O95297), corresponding to amino acid residues around phosphorylated Tyr263.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of PZR only when phosphorylated at Tyr263
  • Cell surface receptor, which is involved in signal transduction processes
  • Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2
  • Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases
  • Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA
  • Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.