Phospho-GAB2 (Tyr643) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5114680-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5114680 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Phospho-GAB2 (Tyr643)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GAB2
Gene Alias
AI463667; D130058I17Rik; GAB2; Grb2 associated binder 2; GRB2 associated binding protein 2; GRB2-associated binder 2; GRB2-associated binding protein 2; GRB2-associated-binding protein 2; GRB3-3; Growth factor receptor bound protein 2-associated protein 2; KIAA0571; p97; PH domain-containing adaptor molecule p97; pp100
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
14389, 84477, 9846
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (PFA fixed), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.
Q9EQH1, Q9UQC2, Q9Z1S8
Gene Symbols
GAB2
Immunogen
A synthesized peptide derived from human GAB2(Accession Q9UQC2), corresponding to amino acid residues around phosphorylated Tyr643.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of Gab2 only when phosphorylated at tyrosine 643
- This gene is a member of the GRB2-associated binding protein (GAB) gene family
- These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein
- They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors
- The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor
- Two alternatively spliced transcripts encoding different isoforms have been described for this gene.