PIPA5114779

SRRM1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5114779-Each-of-1 In Stock ₹ 46,502.50

PIPA5114779 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

SRRM1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SRRM1

Gene Alias

160-KD; AA407769; LOW QUALITY PROTEIN: serine/arginine repetitive matrix protein 1; plenty-of-prolines 101; plenty-of-prolines-101; Pop101; Ser/Arg-related nuclear matrix protein; serine and arginine repetitive matrix 1; serine/arginine repetitive matrix 1; serine/arginine repetitive matrix protein 1; Srm160; SR-related nuclear matrix protein of 160 kDa; SRRM1; wu:fb34f04; wu:fb38b06; zgc:63802

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10250, 51796

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.

Q52KI8, Q8IYB3

Gene Symbols

SRRM1

Immunogen

A synthesized peptide derived from human SRRM1(Accession Q8IYB3), corresponding to amino acid residues P847-K897.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total SRRM1
  • Part of pre- and post-splicing multiprotein mRNP complexes
  • Involved in numerous pre-mRNA processing events
  • Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome
  • Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex
  • Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions
  • Binds RNA and DNA with low sequence specificity and has similar preference for either double- or single-stranded nucleic acid substrates.