PIPA5114791

ZFPM1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5114791-Each-of-1 In Stock ₹ 46,502.50

PIPA5114791 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

ZFPM1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ZFPM1

Gene Alias

FOG; Fog1; FOG-1; friend of GATA 1; friend of GATA protein 1; Friend of GATA-1; ZC2HC11A; ZFN89A; Zfpm1; Zinc finger protein 89A; Zinc finger protein multitype 1; Zinc finger protein ZFPM1; zinc finger protein, FOG family member 1; zinc finger protein, multitype 1; ZNF408; ZNF89A

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

161882, 22761

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.

O35615, Q8IX07

Gene Symbols

ZFPM1

Immunogen

A synthesized peptide derived from human ZFPM1(Accession Q8IX07), corresponding to amino acid residues A651-H701.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total ZFPM1
  • ZFPM1 is a transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation
  • ZFPM1 is an essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3
  • Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context
  • The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1
  • ZFPM1 may be involved in regulation of some genes in gonads
  • ZFPM1 may also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2.