CDK8 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5115001-Each-of-1 | In Stock | ₹ 45,968.50 |
PIPA5115001 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,968.50
GST (18%): ₹ 8,274.33
Total Price: ₹ 54,242.83
Antigen
CDK8
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Cdk8
Gene Alias
Cdk8; CDK8 protein kinase; cell division protein kinase 8; Cell division protein kinase 8-like protein; cyclin dependent kinase 8; cyclin-dependent kinase 8; K35; mediator complex subunit CDK8; Mediator of RNA polymerase II transcription subunit CDK8; MGC126074; MGC126075; protein kinase K35; RGD1560888; wu:fk95h11
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1024, 264064, 498140
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.
P49336, Q8R3L8
Gene Symbols
Cdk8
Immunogen
A synthesized peptide derived from human CDK8(Accession P49336), corresponding to amino acid residues E14-C64.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total CDK8
- CDK8 phosphorylates the carboxy-terminal domain of the largest subunit of RNA polymerase II
- This protein is coexpressed and copurified with Cyclin C
- CDK8 is part of a family of proteins designated as cdks are critical regulators of cell cycle progression
- The prototype member of this family, p34/Cdc 2, and a related protein Cdk 2, function late in the cycle while Cdk 4 and Cdk 6 are critically involved in G1 to S progression
- Because of analogy with yeast Cdk 8, it has been proposed that the human Cdk 8 Cyclin C may interact with RNA polymerase, thus influencing the transcription mechanism(s) that lead to cell division.