BIN1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5116490-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5116490 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
BIN1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
BIN1
Gene Alias
ALP-1; AMPH 2; Amph2; amphiphysin 2; amphiphysin II; amphiphysin IIamph2; amphiphysin-like; amphiphysin-like protein; AMPHL; Bin1; box dependant MYC interacting protein 1; box-dependent myc-interacting protein 1; BRAMP-2; bridging integrator 1; DKFZp547F068; MGC10367; MGC105358; myc box dependent interacting protein 1; myc box-dependent-interacting protein 1; SH3 domain-containing protein 9; SH3P9; similar to bridging integrator 1 isoform 9
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
117028, 274, 30948
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
O00499, O08539, O08839
Gene Symbols
BIN1
Immunogen
Recombinant protein within human BIN1 aa 56-257
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive controls: Rat spleen tissue, SiHa, rat brain tissue, human colon cancer tissue, human spleen tissue, human kidney tissue, mouse skeletal muscle tissue
- This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor
- Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin
- Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process
- Studies in mouse suggest that this gene plays an important role in cardiac muscle development
- Alternate splicing of the gene results in ten transcript variants encoding different isoforms
- Aberrant splice variants expressed in tumor cell lines have also been described.