PIPA5116832
Importin 7 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5116832-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5116832 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Importin 7
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Ipo7
Gene Alias
A330055O14Rik; C330016G14; FLJ14581; Imp7; importin 7; importin-7; IPO7; MGC138673; RAN binding protein 7; RAN-binding protein 7; RanBP7
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10527, 233726, 308939
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
0.58 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.
O95373, Q9EPL8
Gene Symbols
Ipo7
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 900 to the C-terminus of human IPO7 (NP_0063821)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: U-251MG, HepG2, HeLa, Mouse heart, Mouse brain, Rat brain Immunogen sequence: ELGSDEDDID EDGQEYLEIL AKQAGEDGDD EDWEEDDAEE TALEGYSTII DDEDNPVDEY QIFKAIFQTI QNRNPVWYQA LTHGLNEEQR KQLQDIATLA DQRRAAHESK MIEKHGGYKF SAPVVPSSFN FGGPAPGMN The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal
- The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta
- Similar to importin-beta, this protein prevents the activation of RaNULLs GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin
- This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions
- At least four importin beta-like transport receptors, namely importin beta itself, transportin, RanBP5 and RanBP7, directly bind and import ribosomal proteins.