PANK2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5116847-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5116847 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
PANK2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PANK2
Gene Alias
4933409I19Rik; AI642621; C20orf48; Hallervorden-Spatz syndrome; HARP; hPanK2; HSS; NBIA1; PANK2; pantothenate kinase 2; pantothenate kinase 2 (Hallervorden-Spatz syndrome); pantothenate kinase 2, mitochondrial; pantothenate kinase 2, mitochondrial isoform 1 preproprotein; pantothenate kinase 2, mitochondrial-like; pantothenic acid kinase 2; PKAN
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
74450
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
1.52 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.
0
Gene Symbols
PANK2
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 300-400 of human PANK2 (NP_7059022)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: Mouse lung Immunogen sequence: RDKNFSSLHT VFCATGGGAY KFEQDFLTIG DLQLCKLDEL DCLIKGILYI DSVGFNGRSQ CYYFENPADS EKCQKLPFDL KNPYPLLLVN IGSGVSILAV Y Pantothenate kinase is an essential regulatory enzyme in CoA biosynthesis, catalyzing the cytosolic phosphorylation of pantothenate (vitamin B5), N-pantothenoylcysteine, and pantetheine
- CoA is the major acyl carrier, playing a central role in intermediary and fatty acid metabolism
- In both yeast and fly, each with only 1 pantothenate kinase gene, the null mutant is inviable
- Mutations in PANK2 are the cause of pantothenate kinase-associated neurodegeneration (PKAN), formerly known as Hallervorden-Spatz syndrome (HSS)
- PKAN is an autosomal recessive neurodegenerative disorder associated with iron accumulation in the brain
- Mutations in PANK2 are the cause of hypoprebetalipoproteinemia, acanthocytosis, retinitis pigmentosa, and pallidal degeneration (HARP).