NFS1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5117064-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5117064 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
NFS1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NFS1
Gene Alias
AA987187; cysteine desulfurase, mitochondrial; Cysteine desulfurase, mitochondrial-like protein; HUSSY-08; IscS; LOW QUALITY PROTEIN: cysteine desulfurase, mitochondrial; m-Nfs1; m-Nfsl; Nfs1; NFS1 cysteine desulfurase; NFS1 nitrogen fixation 1 homolog; NFS1 nitrogen fixation 1 homolog (S. cerevisiae); NFS1, cysteine desulfurase; Nifs; nifS-like (sic); nitrogen fixation 1 (S. cerevisiae, homolog); nitrogen fixation gene 1; nitrogen fixation gene 1 (S. cerevisiae); nitrogen fixation gene, yeast homolog 1; nitrogen-fixing bacteria S-like protein
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
18041, 84594, 9054
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1.07 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.
Q99P39, Q9Y697, Q9Z1J3
Gene Symbols
NFS1
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 290-457 of human NFS1 (NP_0669233)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: SH-SY5Y, HepG2, BxPC-3, Mouse brain, Mouse liver, Mouse heart, Rat brain, Rat liver, Rat heart Immunogen sequence: GMRSGTVPTP LVVGLGAACE VAQQEMEYDH KRISKLSERL IQNIMKSLPD VVMNGDPKHH YPGCINLSFA YVEGESLLMA LKDVALSSGS ACTSASLEPS YVLRAIGTDE DLAHSSIRFG IGRFTTEEEV DYTVEKCIQH VKRLREMSPL WEMVQDGIDL KSIKWTQH NFS1 (nitrogen fixation 1), also known as NIFS or IscS (cysteine desulfurase), is a member of the class V pyridoxal-phosphate-dependent aminotransferase family
- It localizes to the cytoplasm or mitochondrion depending on which form is generated based on cytosolic pH
- Highest expression levels of NFS1 are found in heart and skeletal muscle
- Lower levels of expression are also found in liver, brain and pancreas
- NFS1 is responsible for catalyzing the removal of sulfur from cysteine to form alanine, thereby supplying the inorganic sulfur for iron-sulfur (Fe-S) clusters
- Fe-S clusters function as essential cofactors in a wide variety of events, including facilitation of electron transfer processes in oxidative phosphorylation, catalysis of enzymatic reactions in aconitase and dehydratases and maintenance of structural integrity in the DNA repair enzyme endonuclease III.