PIPA5117330

ZFP36 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5117330-Each-of-1 In Stock ₹ 46,502.50

PIPA5117330 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

ZFP36

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Zfp36

Gene Alias

G0/G1 switch regulatory protein 24; G0S24; GOS24; growth factor-inducible nuclear protein NUP475; mRNA decay activator protein ZFP36; Nup475; RNF162A; Tax interacting protein; TIS11; TIS11A; TIS11D; TISII; TNF alpha inhibitor; TPA-induced sequence 11; Tristetraprolin; tristetraprolin; LOW QUALITY PROTEIN: mRNA decay activator protein ZFP36; tristetraproline; TTP; Zfp36; zfp-36; ZFP36 ring finger protein; zinc finger protein 36; zinc finger protein 36 homolog; zinc finger protein 36, C3H type, homolog; zinc finger protein, C3H type, 36 homolog

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

22695, 7538

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

2.47 mg/mL

Formulation

PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.

P22893, P26651

Gene Symbols

Zfp36

Immunogen

Recombinant protein encompassing a sequence within the center region of human Tristetraprolin. The exact sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Centrifuge briefly prior to opening
  • ZFP36 is a probable regulatory protein with a novel zinc finger structure involved in regulating the response to growth factors
  • Knockdown of ZFP36 increased both cognate macrophage gene mRNAs and inflammatory tumor necrosis factor protein release
  • Overexpression of ZFP36 resulted in decreased levels of the same genes supporting its role in regulating macrophage gene expression
  • Multiple phosphorylation sites in ZFP36 in mammalian cells were reported
  • ZFP36 can be phosphorylated by JNK as well as by the other members of the greater MAP kinase family
  • Gene expression profiling predicts clinical outcome of prostate cancer
  • Inappropriate ZFP36 production may be one factor that contributes to higher rheumatoid arthritis disease activity.