PIPA5119200

Iduronate 2 Sulfatase Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5119200-Each-of-1 In Stock ₹ 42,408.50

PIPA5119200 - Each of 1

₹ 42,408.50

In Stock

Quantity

1

Base Price: ₹ 42,408.50

GST (18%): ₹ 7,633.53

Total Price: ₹ 50,042.03

Antigen

Iduronate 2 Sulfatase

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Ids

Gene Alias

alpha-L-iduronate sulfate sulfatase; AW214631; Ids; Iduronate 2-sulfatase; iduronate 2-sulfatase (Hunter syndrome); iduronate 2-sulfatase 14 kDa chain; Iduronate 2-sulfatase 42 kDa chain; iduronate sulfatase; iduronate-2-sulfatase; idursulfase; MPS2; SIDS

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3423

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.

P22304

Gene Symbols

Ids

Immunogen

Recombinant protein Iduronate-2-Sulfatase. The antigen corresponds to amino acid range 95-289 of the target protein.

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate
  • Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome
  • Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase
  • Multiple alternatively spliced transcript variants that encode different protein isoforms have been described.