PIPA5122109

CD50 (ICAM-3) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5122109-Each-of-1 In Stock ₹ 14,756.20

PIPA5122109 - Each of 1

₹ 14,756.20

In Stock

Quantity

1

Base Price: ₹ 14,756.20

GST (18%): ₹ 2,656.116

Total Price: ₹ 17,412.316

Antigen

CD50 (ICAM-3)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ICAM3

Gene Alias

CD50; CDw50; ICAM3; ICAM-3; ICAM-R; Intercellular adhesion molecule 3; intercellular adhesion molecule-3

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3385

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

500 μg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.

P32942

Gene Symbols

ICAM3

Immunogen

Recombinant protein Intercellular Adhesion Molecule 3. The antigen corresponds to amino acid range 46-197 of the target protein.

Quantity

20 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • CD50 (intracellular adhesion molecule 3, ICAM-3) is a transmembrane glycoprotein expressed by leukocytes, that serves as a counter-receptor for the lymphocyte function-associated antigen (LFA)-1 integrin
  • Besides functioning as an adhesive molecule that mediates e.g
  • the contact between T cells and antigen presenting cells, ICAM-3 regulates affinity of LFA-1 for ICAM-1 and induces T cell activation and proliferation
  • ICAM-3 plays an essential role in the initiation of the immune response both on T cells and antigen presenting cells and interacts also with CD209 (dendritic cell-specific ICAM-3-grabbing nonintegrin, DC-SIGN), a C-type lectin of dendritic cells and macrophages; this process is involved in dialogue between dendritic cells and granulocytes.