CaMKII gamma Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5122168-Each-of-1 | In Stock | ₹ 17,346.10 |
PIPA5122168 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 17,346.10
GST (18%): ₹ 3,122.298
Total Price: ₹ 20,468.398
Antigen
CaMKII gamma
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CAMK2G
Gene Alias
Ca2+/calmodulin-dependent protein kinase II; calcium/calmodulin dependent protein kinase II gamma; calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma; calcium/calmodulin-dependent protein kinase II gamma; calcium/calmodulin-dependent protein kinase type II gamma chain; calcium/calmodulin-dependent protein kinase type II subunit gamma; CaM kinase II subunit gamma; CAM2; CAMK; CaMK II; CAMK2; CAMK2B; CAMK2D; Camk2g; CAMKB; CAMKD; CAMKG; CAMK-II; caMK-II subunit gamma; caM-kinase II gamma chain
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
171140
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
500 μg/mL
Formulation
PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.
P11730
Gene Symbols
CAMK2G
Immunogen
Recombinant protein Calcium/Calmodulin Dependent Protein Kinase II Gamma. The antigen corresponds to amino acid range 14-301 of the target protein.
Quantity
20 μL
Primary or Secondary
Primary
Target Species
Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplasmic reticulum Ca(2+) transport in skeletal muscle
- In neurons, plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner
- This structural function is required for correct targeting of CaMK2A, which acts downstream of NMDAR to promote dendritic spine and synapse formation and maintain synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning
- In developing hippocampal neurons, promotes arborization of the dendritic tree and in mature neurons, promotes dendritic remodeling
- Participates in the modulation of skeletal muscle function in response to exercise
- In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca(2+) transport and in fast-twitch muscle participates in the control of Ca(2+) release from the SR through phosphorylation of triadin, a ryanodine receptor-coupling factor, and phospholamban (PLN/PLB), an endogenous inhibitor of SERCA2A/ATP2A2.