PIPA5143440
Zika Virus Envelope (strain H/PF/2013) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5143440-Each-of-1 | In Stock | ₹ 39,071.00 |
PIPA5143440 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 39,071.00
GST (18%): ₹ 7,032.78
Total Price: ₹ 46,103.78
Antigen
Zika Virus Envelope (strain H/PF/2013)
Classification
Polyclonal
Conjugate
Unconjugated
Gene Alias
Zika Envelope
Immunogen
Recombinant protein encompassing a sequence within the center region of Zika virus Envelope protein (Zika virus (strain H/PF/2013)). The exact sequence is proprietary.
Quantity
100 μL
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ELISA, Immunocytochemistry, Western Blot
Concentration
1.18 mg/mL
Formulation
PBS with 20% glycerol and 0.025% Proclin 300; pH 7
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Target Species
Virus
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Store as concentrated solution
- Centrifuge briefly prior to opening vial
- Positive control: Zika virus Envelope-transfected 293T, Zika virus Envelope-infected C6/36
- As a member of the Flaviviridae family, ZIKV has a single positive sense RNA genome, which is initially translated as a single polyprotein which is then cleaved post-transitionally into three structural proteins (C, PrM or M, and E) and seven nonstructural (NS) proteins (NS1, NS2A, NS2B, NS3, NS4A, NS4B and NS5)(1)
- The glycosated NS1 forms a homodimer inside the cells and is necessary for viral replication and late in infection (2)
- NS1 is also secreted into the extracellular space as a hexameric lipoprotein particle, which assists the virus in immune evasion and pathogenesis by interacting with components from both innate and adaptive immune systems as well as other host factors (1)
- Reference 1) Song, H.; Qi, J.; Haywood, J.; Shi, Y.; Gao, G.F
- (2016)
- Nat
- Struct
- Mol
- Biol
- 23, 456-458
- 2) Suthar, M.S., Diamond, M.S
- and Gale, M
- Jr
- (2013)
- Nat
- Rev
- Microbiol
- 11, 115-128.