PIPA5143491

Zika Virus NS5 (strain H/PF/2013) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5143491-Each-of-1 In Stock ₹ 39,071.00

PIPA5143491 - Each of 1

₹ 39,071.00

In Stock

Quantity

1

Base Price: ₹ 39,071.00

GST (18%): ₹ 7,032.78

Total Price: ₹ 46,103.78

Antigen

Zika Virus NS5 (strain H/PF/2013)

Classification

Polyclonal

Conjugate

Unconjugated

Gene Alias

NS5; NS5 protein

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of Zika virus NS5 protein (Zika virus (strain H/PF/2013)). The exact sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

0.35 mg/mL

Formulation

PBS with 20% glycerol and 0.025% Proclin 300; pH 7

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Target Species

Virus

Product Type

Antibody

Isotype

IgG

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Description

  • Store as concentrated solution
  • Centrifuge briefly prior to opening vial
  • Zika Virus nonstructural protein 5 (NS5) interacts with the host retinoic acid-inducible gene I (RIG-I), which is an essential signaling molecule for defending pathogen infections
  • NS5 subsequently represses K63-linked polyubiquitination of RIG-I, attenuates the phosphorylation and nuclear translocation of interferon regulatory factor 3 (IRF3), and inhibits the expression and production of interferon-beta (IFN-beta), thus restricting the RIG-I signaling pathway.