PIPA5143685

Phospho-MAPRE3 (Ser176) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5143685-Each-of-1 In Stock ₹ 45,879.50

PIPA5143685 - Each of 1

₹ 45,879.50

In Stock

Quantity

1

Base Price: ₹ 45,879.50

GST (18%): ₹ 8,258.31

Total Price: ₹ 54,137.81

Antigen

Phospho-MAPRE3 (Ser176)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MAPRE3

Gene Alias

AI790651; APC binding protein; EB1 protein family member 3; EB2; EB3; EBF3; EBF3-S; End-binding protein 3; Mapre3; microtubule associated protein RP/EB family member 3; microtubule-associated protein RP/EB family member 3; microtubule-associated protein, RP/EB family, member 3; RP3

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100732, 22924, 298848

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG

Applications

Western Blot

Concentration

Lot-Specific

Formulation

PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.

Q5XIT1, Q6PER3, Q9UPY8

Gene Symbols

MAPRE3

Immunogen

Phospho-EB3 (Ser-176) synthetic peptide (coupled to KLH) corresponding to amino acid residues surrounding serine 176 in human EB3. This peptide sequence is highly conserved in mouse and rat EB3. This site is conserved in EB2 but the neighboring amino acids are not well conserved.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

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Description

  • This antibody was cross-absorbed to unphospho-EB3 (Ser-176), before affinity purification using phospho-EB3 (Ser-176) peptide (without carrier)
  • The antibody detects a 32 kDa* protein corresponding to the apparent molecular mass of phosphorylated EB3 on SDS-PAGE immunoblots of mouse brain
  • This reactivity is significantly reduced after lambda phosphatase treatment
  • EB3 is a 282 amino acid homologue of EB1, a protein known to bind APC (adenomatous polyposis coli)
  • It has been shown to bind to tubulin in vitro and microtubules in vivo
  • Northern blotting shows expressions to be mainly in brain, and to a lesser degree in muscle
  • EB3 interacts with APCL, a homologue of the tumor suppressor APC, and this interaction may be involved in the stabilization or extension of microtubules.