PIPA5143868

CALM Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5143868-Each-of-1 In Stock ₹ 35,422.00

PIPA5143868 - Each of 1

₹ 35,422.00

In Stock

Quantity

1

Base Price: ₹ 35,422.00

GST (18%): ₹ 6,375.96

Total Price: ₹ 41,797.96

Antigen

CALM

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Picalm

Gene Alias

CALM; Clathrin assembly lymphoid myeloid leukemia; clathrin assembly lymphoid myeloid leukemia protein; clathrin-assembly lymphoid leukemia protein; clathrin-assembly lymphoid myeloid leukemia protein; CLTH; fit1; fit-1; LAP; mKIAA4114; PAP180; phosphatidylinositol binding clathrin assembly protein; phosphatidylinositol-binding clathrin assembly protein; PICALM; rCALM

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

233489, 8301, 89816

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG

Applications

ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

500 μg/mL

Formulation

PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.

O55012, Q13492, Q7M6Y3

Gene Symbols

Picalm

Immunogen

E.coli-derived human PICALM recombinant protein (Position: M1-M652).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Lyophilized

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Description

  • Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL
  • PICALM, also known as the clathrin assembly lymphoid myeloid leukemia (CALM) protein, co-localizes with clathrin at clathrin-coated areas of the plasma membrane and in the Golgi area, and is thought to be an important component of the coated pit internalization machinery
  • Fusion proteins involving PICALM have been implicated in acute myeloid and T-cell acute lymphoblastic leukemia
  • PICALM is also expressed in neurons and is present at the synapse where it facilitates the endocytosis of the synaptic vesicle protein VAMP2
  • Recent studies have identified variants of PICALM associated with Alzheimer's disease and have suggested this protein may play a role in the endocytosis and recycling of the amyloid protein precursor (APP).