PIPA5143963
TNNI1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5143963-Each-of-1 | In Stock | ₹ 35,422.00 |
PIPA5143963 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 35,422.00
GST (18%): ₹ 6,375.96
Total Price: ₹ 41,797.96
Antigen
TNNI1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TNNI1
Gene Alias
SSTNI, TNN1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
7135
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
500 μg/mL
Formulation
PBS with 4MG trehalose and no preservative
Gene Accession No.
P19237
Gene Symbols
TNNI1
Immunogen
A synthetic peptide corresponding to a sequence of human TNNI1 (REAEKVRYLAERIPTLQTR).
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Lyophilized
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Description
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL
- Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles
- Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle
- TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation
- The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac
- The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue
- This gene encodes the Troponin-I-skeletal-slow-twitch protein
- This gene is expressed in cardiac and skeletal muscle during early development but is restricted to slow-twitch skeletal muscle fibers in adults
- The encoded protein prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes.