PIPA515456

PFKFB3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA515456-Each-of-1 In Stock ₹ 46,591.50

PIPA515456 - Each of 1

₹ 46,591.50

In Stock

Quantity

1

Base Price: ₹ 46,591.50

GST (18%): ₹ 8,386.47

Total Price: ₹ 54,977.97

Antigen

PFKFB3

Classification

Polyclonal

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

Q16875

Gene Symbols

PFKFB3

Immunogen

KLH conjugated synthetic peptide between 454-484 amino acids from the C-terminal region of human PFKFB3

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Gene

PFKFB3

Gene Alias

6-biphosphatase 3; 6PF-2-K/Fru-2,6-P2ase 3; 6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme; 6PF-2-K/Fru-2,6-P2ASE brain-type isozyme; 6-phosphofructo-2-kinase; 6-phosphofructo-2-kinase/ fructose-2,6-bisphosphatase; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3; E330010H22Rik; Fructose-2; Fructose-2,6-bisphosphatase; fructose-6-phosphate,2-kinase/fructose-2, 6-bisphosphatase; inducible 6-phosphofructo-2-kinase; inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase; IPFK2; iPFK-2; PFK/FBPase 3; PFK2; PFKFB3; RB2K; renal carcinoma antigen NY-REN-56; RP11-298K24.3; uPFK-2

Host Species

Rabbit

Purification Method

Ammonium sulfate precipitation, Size-exclusion - Dialysis

Regulatory Status

RUO

Gene ID (Entrez)

5209

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • This antibody is predicted to react with rat based on sequence homology
  • The protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes
  • The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate (F2,6BP), and a fructose-2,6-biphosphatase activity that catalyzes the degradation of F2,6BP
  • This protein is required for cell cycle progression and prevention of apoptosis
  • It functions as a regulator of cyclin-dependent kinase 1, linking glucose metabolism to cell proliferation and survival in tumor cells
  • Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.