Acetyl-CBP/p300 (Lys1499, Lys1535) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA516185-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA516185 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
Acetyl-CBP/p300 (Lys1499, Lys1535)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
EP300
Gene Alias
A430090G16; A730011L11; AW558298; CBP; CBP/p300; CREB binding protein; CREB-binding protein; Crebbp; E1A binding protein p300; E1A-associated protein p300; E1A-binding protein, 300kD; EP300; Histone acetyltransferase p300; Histone butyryltransferase p300; Histone crotonyltransferase p300; KAT3A; KAT3B; p300; p300 HAT; p300/CBP; Protein propionyltransferase p300; RSTS; RSTS2; RTS
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
12914, 1387, 170915, 2033, 328572, 54244
Content And Storage
-20°C
Form
Liquid
Applications
Immunoprecipitation, Western Blot
Concentration
754 μg/mL
Formulation
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.
B2RWS6, P45481, Q09472, Q6JHU9, Q92793
Gene Symbols
CREBBP, EP300
Immunogen
Synthetic acetylated peptide corresponding to residues surrounding Lys1535 of human CBP
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- It is not recommended to aliquot this antibody
- This gene is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors
- First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition
- The protein encoded by this gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex
- This protein acetylates both histone and non-histone proteins
- This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain
- Mutations in this gene cause Rubinstein-Taybi syndrome (RTS)
- Chromosomal translocations involving this gene have been associated with acute myeloid leukemia
- Alternative splicing results in multiple transcript variants encoding different isoforms.