Phospho-Vimentin (Ser56) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA517235-Each-of-1 | In Stock | ₹ 45,968.50 |
PIPA517235 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,968.50
GST (18%): ₹ 8,274.33
Total Price: ₹ 54,242.83
Antigen
Phospho-Vimentin (Ser56)
Classification
Polyclonal
Formulation
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.
P08670, P20152
Gene Symbols
Vim
Immunogen
Synthetic phosphopeptide corresponding to residues surrounding pSer56 of human vimentin
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Western Blot
Conjugate
Unconjugated
Gene
Vim
Gene Alias
cb28; class-III intermediate microfilament; CTRCT30; epididymis luminal protein 113; FLJ36605; HEL113; intermediate filament; intermediate filament protein; RP11-124N14.1; similar to vimentin; VIM; VIME; Vimentin; vimentin C-terminus
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
22352, 7431
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- It is not recommended to aliquot this antibody
- Vimentin is a developmentally regulated intermediate filament protein (IFP) found in cells of mesenchymal origin
- It is believed to be involved with the intracellular transport of proteins between the nucleus and plasma membrane
- Unlike other IFP proteins, vimentin is expressed, along with desmin, during the early stages of cellular development
- During the development process, vimentin is exchanged for new, tissue-specific IFPs
- Vimentin has been implicated to be involved in the rate of steroid synthesis via its role as a storage network for steroidogenic cholesterol containing lipid droplets
- Vimentin phosphorylation by a protein kinase causes the breakdown of intermediate filaments and activation of an ATP and myosin light chain dependent contractile event
- This results in cytoskeletal changes that facilitate the interaction of the lipid droplets within mitochondria, and subsequent transport of cholesterol to the organelles leading to an increase in steroid synthesis.