BACE2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA519951-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA519951 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
BACE2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
BACE2
Gene Alias
1110059C24Rik; 56 kDa aspartic-like protease; AEPLC; AI850424; ALP56; ARP1; asp 1; ASP1; ASP21; Aspartic-like protease 56 kDa; Aspartyl protease 1; Bace2; BAE2; be; beta secretase 2; Beta-secretase 2; beta-site amyloid beta A4 precursor protein-cleaving enzyme 2; beta-site amyloid precursor protein cleaving enzyme 2; Beta-site APP cleaving enzyme 2; beta-site APP-cleaving enzyme 2; CDA13; CEAP1; Down region aspartic protease; Down syndrome region aspartic protease; DRAP; memapsin 1; memapsin-1; Membrane-associated aspartic protease 1; theta-secretase; transmembrane aspartic proteinase Asp1; UNQ418/PRO852
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
25825, 288227
Content And Storage
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
Q6IE75, Q9Y5Z0
Gene Symbols
BACE2
Immunogen
A peptide corresponding to amino acids near the carboxy terminus of human BACE2.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- A suggested positive control is human heart tissue lysate
- PA5-19951 can be used with blocking peptide PEP-0076
- BACE2 or Beta Secretase 2 is responsible for the proteolytic processing of the amyloid precursor protein (APP)
- BACE2 cleaves APP between residues 690 and 691
- This cleavage leads to the generation and extracellular release of beta-cleaved soluble APP
- BACE2 is also know to cleave APP between residues 671 and 672
- Accumulation of APP is a signature of Alzheimer disease and frequent complication of adult Down syndrome patients.