PIPA520273

TIP47 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA520273-Each-of-1 In Stock ₹ 48,905.50

PIPA520273 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

TIP47

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PLIN3

Gene Alias

1300012C15Rik; 47 kDa mannose 6-phosphate receptor-binding protein; 47 kDa MPR-binding protein; 47 kDa tail interaction protein; cargo selection protein TIP47; M6prbp1; mannose 6 phosphate receptor binding protein 1; mannose-6-phosphate receptor binding protein 1; mannose-6-phosphate receptor-binding protein 1; MGC11117; MGC2012; perilipin 3; perilipin-3; Placental protein 17; Plin3; PP17; tail-interacting protein, 47 kD; testicular tissue protein Li 114; TIP47; Unknown (protein for MGC:128897)

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10226, 316130, 66905

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

O60664, Q9DBG5

Gene Symbols

PLIN3

Immunogen

A 14 amino acid peptide from near the amino terminus of human TIP47.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • A suggested positive control is EL4 cell lysate
  • PA5-20273 can be used with blocking peptide PEP-0388
  • TIP47 has been described as cargo protein involved in the trafficking of the mannose-6-phosphate receptor between endosomes and the Golgi complex
  • Mannose 6-phophate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex
  • The protein encoded by this gene interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs and is required for endosome to Golgi transport
  • This protein also binds directly to the GTPase RAB9, a member of the RAS oncogene family
  • The interaction with RAB9 has been shown to increase the affinity of this protein for its cargo
  • TIP47 has been localized in milk fat globule membranes of human and bovine origin
  • It has been described as a placental protein, as well
  • Increased amounts of TIP47 are secreted into circulation of cervix carcinoma patients
  • Therefore, this protein is probably significant as an oncodevelopmental marker.