Prosapip2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA520814-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA520814 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Prosapip2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TBKBP1
Gene Alias
3110043L15Rik; KIAA0775; Prosapip2; Protein ProSAPiP2; RGD:631328}; Similar to NAP1 TBK1 adapter; Sintbad; TANK-binding kinase 1-binding protein 1; TBK1 binding protein 1; TBK1-binding protein 1; Tbkbp1; tbkbp1 {ECO:0000312
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
266764, 73174, 9755
Content And Storage
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
A2A9T0, A7MCY6, Q6DG50
Gene Symbols
TBKBP1
Immunogen
A 16 amino acid peptide from near the carboxy terminus of human Prosapip2.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- A suggested positive control is rat liver tissue lysate
- PA5-20814 can be used with blocking peptide PEP-0928
- Prosapip2 (TBKBP1) is essential for signal transduction during viral infection thus plays a major role in the TNF/NF-kappa-B pathway
- It is an adaptor protein that constitutively binds TBK1 (TANK-binding kinase) and IKBKE and may play a role in antiviral innate immunity
- Prosapip2 is a 615 amino acid adaptor protein belonging to the fibrillar collagen family, consisting of trimers of identical alpha 1 chains which are linked to each other by interchain disulfide bonds
- It has a ubiquitous expression with highest levels in ovary, followed by the neuronal system
- Prosapip2 binds to TBK1 and helps in the activation of IRF3 which controls the expression of antiviral genes during infection
- Recent studies show that Prosapip2 is an interaction partner of ProSAP2/Shank3 and actin, suggesting a role as a linker molecule between postsynaptic density and the cytoskeleton.