PIPA520829

ACBD3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA520829-Each-of-1 In Stock ₹ 46,057.50

PIPA520829 - Each of 1

₹ 46,057.50

In Stock

Quantity

1

Base Price: ₹ 46,057.50

GST (18%): ₹ 8,290.35

Total Price: ₹ 54,347.85

Antigen

ACBD3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Acbd3

Gene Alias

60kDa; 8430407O11Rik; Acbd3; acyl-CoA binding domain containing 3; acyl-CoA-binding domain-containing protein 3; acyl-Coenzyme A binding domain containing 3; D1Ertd10e; DAP; DMT1-associated protein; fa20g08; GCP60; Gocap1; golgi complex associated protein 1, 60 kDa; golgi complex associated protein 1, 60kDa; golgi complex-associated protein 1; Golgi phosphoprotein 1; Golgi resident protein GCP60; Golgi resident protein GCP60, N-terminally processed; GOLPH1; neurotrophin receptor alike death domain protein; p75-like apoptosis-inducing death domain protein; Pap7; PBR- and PKA-associated protein 7; PBR associated protein; Peripheral benzodiazepine receptor-associated protein PAP7; peripherial benzodiazepine receptor associated protein; PKA (RIalpha)-associated protein; si:dkey-267p15.1; wu:fa20g08; zgc:66303

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

64746

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

Q9H3P7

Gene Symbols

Acbd3

Immunogen

A 16 amino acid peptide from near the amino terminus of human GOLPH1.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • A suggested positive control is K562 cell lysate
  • PA5-20829 can be used with blocking peptide PEP-0943
  • GOLPH1, also known as GCP60, was initially identified as a Golgi protein that can interact with the integral membrane protein giantin and is thought to be involved in the maintenance of the Golgi structure
  • GOLPH1 has also been shown to interact with other Golgi proteins such as Golgin-160, a Golgi protein that can be cleaved by caspases-2, -3, and -7, leading to the nuclear localization of Golgin-160
  • GOLPH1 interaction with the Golgin-160 fragments is stronger than that with the intact Golgin-160, with its interaction regulated by the oxidation state of Cys-463 within GOLPH1, suggesting that the nuclear localization of the caspase-cleaved Golgin-160 fragments is a highly coordinated event
  • GOLPH1 has also been found to interact with Numb, a cytosolic signaling protein that mediates asymetric cell division of neural progenitor cells to a daughter progenitor cell and a neuron, suggesting that Golgi fragmentation and reconstitution during the cell cycle differentially regulate Numb signaling through changes in GOLPH1 subcellular distribution and may couple cell fate with cell cycle progression.