PIPA521123

CD150 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA521123-Each-of-1 In Stock ₹ 49,350.50

PIPA521123 - Each of 1

₹ 49,350.50

In Stock

Quantity

1

Base Price: ₹ 49,350.50

GST (18%): ₹ 8,883.09

Total Price: ₹ 58,233.59

Antigen

CD150

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Slamf1

Gene Alias

4933415F16; AA177906; CD150; CD150 antigen; CDw150; ESTM51; IPO-3; RGD1560634; signaling lymphocyte activation molecule; signaling lymphocytic activation molecule; signaling lymphocytic activation molecule family member 1; Slam; SLAM family member 1; Slamf1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

27218, 498286, 6504

Content And Storage

4° C

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

Q13291, Q9QUM4

Gene Symbols

Slamf1

Immunogen

A 15 amino acid peptide near the amino terminus of human SLAMF1.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • A suggested positive control is rat colon lysate
  • PA5-21123 can be used with blocking peptide PEP-1237
  • CD150 (SLAM, Signaling Lymphocyte Activation Molecule) belongs to the immunoglobulin gene superfamily, and is involved in T cell stimulation
  • SLAM is constitutively expressed on peripheral blood memory T cells, T cell clones, immature thymocytes, and a proportion of B cells, and is rapidly induced on naive T cells after activation
  • Activated B cells express the membrane bound form, the soluble form and the cytoplasmic isoforms of SLAM
  • It is suggested that signalling through homophilic SLAM-SLAM binding during B to B and B to T cell interactions enhances the expansion and differentiation of activated B cells
  • Reports suggest that the extracellular domain of CD150 is the receptor for the measles virus and acts as a co-activator on T cells and B cells
  • Moreover, CD150 is thought to interact with SH2D1A and with PTPN11 via its cytoplasmic domain
  • Mutations CD150 gene may be associated with X-linked lympho-proliferative disease (XLP).