PIPA525130

CMPK2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA525130-Each-of-1 In Stock ₹ 48,905.50

PIPA525130 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

CMPK2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CMPK2

Gene Alias

1200004E04Rik; Cmpk2; cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial; cytidine/uridine monophosphate kinase 2; cytidylate kinase 2; mitochondrial UMP-CMP kinase; NDK; Nucleoside-diphosphate kinase; TDKI; thymidine monophosphate kinase 2; thymidylate kinase family LPS-inducible member; thymidylate kinase homologue; thymidylate kinase LPS-inducible member; TMPK2; Tyki; UMP/CMP kinase; UMP-CMP kinase 2, mitochondrial; UMP-CMPK2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

129607

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

Q5EBM0

Gene Symbols

CMPK2

Immunogen

KLH conjugated synthetic peptide between 142-170 amino acids from the central region of human CMPK2

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • UMP-CMP kinase 2 (CMPK2) is the first nucleoside monophosphate kinase that has been identified in human mitochondria
  • It is a component of the salvage pathway for nucleotide synthesis that may participate in terminal differentiation of monocytic cells
  • There are two distinct domains of CMPK2: the N-terminal domain with unknown function and the C-terminal domain with the kinase function, suggesting that CMPK2 may be a bifunctional protein with other biological functions in addition to its UMP-CMP kinase activity
  • CMPK2 may participate in dUTP and dCTP synthesis and is responsible for phosphorylation of dCMP and dUMP in mitochondria
  • CMPK2 is actively involved in macrophage activation and the inflammatory response.