PIPA525808

Brevican Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA525808-Each-of-1 In Stock ₹ 46,502.50

PIPA525808 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

Brevican

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Bcan

Gene Alias

ALPBRE; Bcan; Behab; Brain-enriched hyaluronan-binding protein; brevican; brevican (brain specific proteoglycan in the aggrecan family); brevican core protein; Chondroitin sulfate proteoglycan 7; chondroitin sulfate proteoglycan BEHAB; CSPG7; UNQ2525/PRO6018

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

63827

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

Q96GW7

Gene Symbols

Bcan

Immunogen

KLH conjugated synthetic peptide between 715-741 amino acids from the C-terminal region of human BCAN

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is predicted to react with bovine based on sequence homology
  • Brevican is the most abundant chondroitin sulfate proteoglycan in the extracellular matrix of the adult brain
  • It is a member of the lectican family of aggregating extracellular matrix proteoglycans that bear chondroitin sulfate (CS) chains
  • It is highly expressed in the central nervous system and is thought to stabilize synapses and inhibit neural plasticity
  • Brevican is secreted from astrocytes and neurons as a 145 kD core protein that bears up to three, covalently-linked, CS chains
  • It is also is secreted as a 145 kD core protein without CS chains
  • When cleaved by extracellular glutamyl endopeptidases, the ADAMTSs, a 55 kD N-terminal fragment is formed that contains the unique C terminal epitope EAMESE.