ESRRB Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA526070-Each-of-1 | In Stock | ₹ 48,816.50 |
PIPA526070 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,816.50
GST (18%): ₹ 8,786.97
Total Price: ₹ 57,603.47
Antigen
ESRRB
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ESRRB
Gene Alias
DFNB35; ERR beta-2; ERR2; Err-2; ERRb; ERRB2; ERRbeta; ERR-beta; ERRbeta-2; ESRL2; ESRRB; estrogen receptor related 2; estrogen receptor-like 2; estrogen related receptor beta; estrogen related receptor, beta; estrogen-related nuclear receptor beta; estrogen-related receptor beta; estrogen-related receptor, beta; Estrrb; NR3B2; nuclear receptor ERRB2; nuclear receptor subfamily 3 group B member 2; orphan nuclear receptor; steroid hormone receptor ERR2
Host Species
Rabbit
Purification Method
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status
RUO
Gene ID (Entrez)
2103
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Concentration
2 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
O95718
Gene Symbols
ESRRB
Immunogen
KLH conjugated synthetic peptide between 275-305 amino acids from the central region of human ESRRB
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- ESRRB (steroid hormone receptor ERR2) plays a role in maintenance of self-renewal and pluripotency of embryonic and trophoblast stem cells through different signaling pathways including FGF signaling pathway and Wnt signaling pathways
- Upon FGF signaling pathway activation ESRRB interacts with KDM1A by directly binding to enhancer sites of ELF5 and EOMES and activates their transcription leading to self-renewal of trophoblast stem cells
- ESSRB also regulates expression of multiple rod-specific genes and is required for survival of this cell type
- Defects in the gene can cause deafness, autosomal recessive, 35 (DFNB35).