p130Cas Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA527225-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA527225 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
p130Cas
Classification
Polyclonal
Conjugate
Unconjugated
Gene
BCAR1
Gene Alias
AI385681; BCA1; Bcar1; BCAR1 scaffold protein, Cas family member; BCAR1, Cas family scaffold protein; BCAR1, Cas family scaffolding protein; breast cancer anti-estrogen resistance 1; breast cancer anti-estrogen resistance protein 1; Cas; Cas scaffolding protein family member 1; CAS1; CASS1; CRKAS; CRK-associated substrate; Crk-associated substrate p130Cas; OTTHUMP00000174941; p130 Cas; P130CAS; p130Cas (pTyr410); p130Cas (pY410); p130Cas phospho; phospho p130Cas; v-crk-associated tyrosine kinase substrate
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
12927, 25414, 9564
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration
0.379 mg/mL
Formulation
PBS with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
P56945, Q61140, Q63767
Gene Symbols
BCAR1
Immunogen
Recombinant fragment corresponding to a region within amino acids 250 and 710 of Human BCAR1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: H1299, NIH-3T3, 293T, p130Cas shRNA-transfected 293T
- Predicted reactivity: Mouse (88%), Rat (88%), Bovine (88%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- The p130Cas (Cas for Crk-associated substrate) is a common cellular target of phosphorylation signal via v-Crk and v-Src oncoproteins
- p130Cas has a unique structure that contains a Src homology (SH)-3 domain followed by multiple YXXP motifs and a proline-rich regionp130Cas is implicated in a variety of biological processes including cell adhesion, cell migration, growth factor stimulation, cytokine receptor engagement and bacterial infection
- Physiological functions of p130Cas include cardiovascular development, actin filament assembly and Src-induced cell transformation.