PRAK Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA528304-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA528304 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
PRAK
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MAPKAPK5
Gene Alias
MAP kinase-activated protein kinase 5; MAPK-activated protein kinase 5; MAPKAP kinase 5; Mapkapk5; MAPKAP-K5; MAPKAPK-5; mitogen-activated protein kinase-activated protein kinase 5; MK5; MK-5; p38-regulated/activated protein kinase; PRAK
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
8550
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q8IW41
Gene Symbols
MAPKAPK5
Immunogen
Recombinant fragment corresponding to a region within amino acids 1 and 304 of Human PRAK
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: HepG2
- Predicted reactivity: Mouse (98%), Rat (97%), Zebrafish (94%), Pig (98%), Chicken (97%), Rhesus Monkey (100%), Bovine (98%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- MAPKAPK5 (PRAK) is activated in response to cellular stress and pro-inflammatory cytokines
- Activity of this kinase is regulated by p38 alpha and p38 beta
- The protein encoded by PRAK is a member of the serine/threonine kinase family
- In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta
- In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites
- Two alternately spliced transcript variants of PRAK encoding distinct isoforms have been reported.