PIPA528587

MAPK15 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA528587-Each-of-1 In Stock ₹ 46,413.50

PIPA528587 - Each of 1

₹ 46,413.50

In Stock

Quantity

1

Base Price: ₹ 46,413.50

GST (18%): ₹ 8,354.43

Total Price: ₹ 54,767.93

Antigen

MAPK15

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MAPK15

Gene Alias

BC048082; EC 2.7.11.24; ERK7; ERK-7; ERK8; ERK-8; extracellular regulated kinase 8 delta; extracellular signal regulated kinase 8; extracellular signal-regulated kinase 7; Extracellular signal-regulated kinase 8; MAP kinase 15; MAPK 15; Mapk15; Mitogen-activated protein kinase 15

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

225689

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

Q8TD08

Gene Symbols

MAPK15

Immunogen

Recombinant protein fragment corresponding to a region within amino acids 1 and 245 of Human MAPK15

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: HeLaS3
  • Predicted reactivity: Human (93%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • The ERKs are a subfamily of the MAPKs that have been implicated in cell growth and differentiation
  • Extracellular signal-regulated kinase 8 (Erk8) is a large MAP kinase whose activity is controlled by serum and the c-Src non-receptor tyrosine kinase
  • ERK8 down-regulates transactivation of the glucocorticoid receptor through Hic-5 and can negatively regulate transcriptional co-activation of androgen receptor and GRalpha by Hic-5 in a kinase-independent manner, suggesting a broader role for ERK8 in the regulation of nuclear receptors beyond estrogen receptor alpha
  • Erk8 is a novel effector of RET/PTC3 and, therefore, RET biological functions.