PIPA528835

CD122 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA528835-Each-of-1 In Stock ₹ 49,706.50

PIPA528835 - Each of 1

₹ 49,706.50

In Stock

Quantity

1

Base Price: ₹ 49,706.50

GST (18%): ₹ 8,947.17

Total Price: ₹ 58,653.67

Antigen

CD122

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Il2rb

Gene Alias

CD122; CD122 antigen; high affinity IL-2 receptor beta subunit; high affinity IL-2 receptor subunit beta; IL-15 receptor beta chain; IL15RB; IL15Rbeta; IL-15Rbeta; IL-2 receptor beta chain; IL-2 receptor subunit beta; IL-2/15 receptor-beta; Il-2/15Rbeta; IL-2R subunit beta; IL2RB; IL-2RB; IL2RBC; Il-2Rbeta; interleukin 15 receptor, beta; interleukin 2 receptor subunit beta; interleukin 2 receptor, beta; interleukin 2 receptor, beta chain; Interleukin-15 receptor subunit beta; Interleukin-2 receptor subunit beta; p70; p70-75; p75

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3560

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

P14784

Gene Symbols

Il2rb

Immunogen

Synthetic peptide corresponding to a region within amino acids 487 and 551 of Human IL2 Receptor beta

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: Raji
  • Predicted reactivity: Chimpanzee (100%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • CD122 (Interleukin 2 receptor) is involved in T cell-mediated immune responses, primarily expressed in the hematopoietic system and is present in 3 forms
  • The low affinity form of CD122 is a monomer of the alpha subunit and is not involved in signal transduction
  • The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer
  • Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from CD122
  • The protein encoded by the CD122 gene represents the beta subunit and is a type I membrane protein
  • Diseases associate with CD122 protein dysfunction include oligoarticular juvenile idiopathic arthritis and rheumatoid factor negative juvenile idiopathic arthritis.