PIPA528947

4EBP1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA528947-Each-of-1 In Stock ₹ 46,502.50

PIPA528947 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

4EBP1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

EIF4EBP1

Gene Alias

4EBP1; 4E-BP1; AA959816; BP-1; eIF4E-binding protein 1; EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; MGC431; MGC4316; P/OKCL.6; PHAS-1; PHAS-I; Phosphorylated heat- and acid-stable protein regulated by insulin 1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

116636, 1978

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.

Q13541, Q62622

Gene Symbols

EIF4EBP1

Immunogen

Full length human 4E-BP1 Recombinant protein.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: HeLa, H1299, HCT116, NB4, HL60
  • Predicted reactivity: Mouse (90%), Rat (92%), Pig (90%), Bovine (92%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • This gene encodes one member of a family of translation repressor proteins
  • The protein directly interacts with eukaryotic translation initiation factor 4E, which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs
  • Interaction of this protein with eIF4E inhibits complex assembly and represses translation
  • This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.