PIPA529148

APC11 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA529148-Each-of-1 In Stock ₹ 46,591.50

PIPA529148 - Each of 1

₹ 46,591.50

In Stock

Quantity

1

Base Price: ₹ 46,591.50

GST (18%): ₹ 8,386.47

Total Price: ₹ 54,977.97

Antigen

APC11

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ANAPC11

Gene Alias

1110011I19Rik; Anapc11; anaphase promoting complex subunit 11; anaphase promoting complex subunit 11 (yeast APC11 homolog); anaphase promoting complex subunit 11 homolog; anaphase-promoting complex subunit 11; APC11; APC11 anaphase promoting complex subunit 11 homolog; Apc11p; Cyclosome subunit 11; hepatocellular carcinoma-associated RING finger protein; HSPC214; R75218; RGD1561880

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

51529

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

Q9NYG5

Gene Symbols

ANAPC11

Immunogen

Synthetic peptide corresponding to a region within amino acids 26 and 84 of Human Apc11

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: 293T, H1299, HeLaS3, HepG2, Molt-4, Raji
  • Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (100%), Xenopus laevis (100%), Rhesus Monkey (100%), Bovine (100%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Together with the cullin protein ANAPC2, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle
  • The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains
  • May recruit the E2 ubiquitin-conjugating enzymes to the complex
  • [UniProt]