Cdc23 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA529218-Each-of-1 | In Stock | ₹ 47,036.50 |
PIPA529218 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,036.50
GST (18%): ₹ 8,466.57
Total Price: ₹ 55,503.07
Antigen
Cdc23
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Cdc23
Gene Alias
6030435O18; ANAPC8; anaphase promoting complex subunit 8; anaphase-promoting complex subunit 8; APC8; CDC23; CDC23 (cell division cycle 23, yeast, homolog); CDC23 cell division cycle 23; cell division cycle 23; cell division cycle 23 homolog; cell division cycle protein 23; cell division cycle protein 23 homolog; CUT23; cyclosome subunit 8; D18Ertd243e; zgc:56013
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
8697
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.53 mg/mL
Formulation
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q9UJX2
Gene Symbols
Cdc23
Immunogen
Recombinant fragment corresponding to a region within amino acids 129 and 413 of Human CDC23
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: H1299, HeLa, HepG2
- Predicted reactivity: Mouse (99%), Rat (99%), Zebrafish (84%), Xenopus laevis (93%), Pig (100%), Rhesus Monkey (100%), Bovine (100%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction
- The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s)
- Ubr2 (Ubiquitin-protein ligase E3-alpha-2), also known as N-recognin-2, is a 1755 amino acid protein that contains one UBR-type zinc finger and one RING-type zinc finger
- Participating in protein modification events within the N-end rule pathway, Ubr2 functions as an E3 ubiquitin-protein ligase that recognizes and binds proteins that contain destabilizing N-terminal residues, thereby leading to their ubiquitination and subsequent degradation
- Mice lacking Ubr2 are infertile due to defects in male meiosis.