PIPA529201
APC10 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA529201-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA529201 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
APC10
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ANAPC10
Gene Alias
1500026N15Rik; A830003M23Rik; ANAPC10; anaphase promoting complex subunit 10; anaphase-promoting complex subunit 10; APC10; cyclosome subunit 10; DKFZp564L0562; DOC1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10393
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q9UM13
Gene Symbols
ANAPC10
Immunogen
Full length human Apc10 Recombinant protein.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: MCF-7
- Predicted reactivity: Mouse (99%), Rat (99%), Zebrafish (90%), Xenopus laevis (94%), Pig (99%), Chicken (97%), Bovine (99%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis
- APC10 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle
- APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence
- The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex
- It has been suggested that APC10 plays a role to regulate the binding of specific substrates to the APC/C complex, similar to that of coactivators.