ERCC1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA529158-Each-of-1 | In Stock | ₹ 51,620.00 |
PIPA529158 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,620.00
GST (18%): ₹ 9,291.60
Total Price: ₹ 60,911.60
Antigen
ERCC1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ERCC1
Gene Alias
COFS4; DNA excision repair protein ERCC-1; ERCC excision repair 1, endonuclease non-catalytic subunit; Ercc1; Ercc-1; excision repair cross-complementation group 1; excision repair cross-complementing 1; excision repair cross-complementing rodent repair deficiency, complementation group 1; excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence); hypothetical protein LOC405807; RAD10; UV20; zgc:77511
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
2067
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
P07992
Gene Symbols
ERCC1
Immunogen
Recombinant fragment corresponding to a region within amino acids 1 and 297 of Human ERCC1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: HeLa, KOSC3
- Predicted reactivity: Mouse (85%), Rat (83%), Pig (89%), Chimpanzee (100%), Bovine (88%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- ERCC1 is a non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair
- It is responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL)
- It participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure
- ERCC1 is also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4
- (Uniprot)