SP1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA529165-Each-of-1 | In Stock | ₹ 52,688.00 |
PIPA529165 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,688.00
GST (18%): ₹ 9,483.84
Total Price: ₹ 62,171.84
Antigen
SP1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SP1
Gene Alias
1110003E12Rik; AA450830; AI845540; HGNC:11205; SP1; Sp1 transcription factor; Sp1-1; specificity protein 1; trans-acting transcription factor 1; transcription factor Sp1; TSFP1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
6667
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration
0.22 mg/mL
Formulation
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.
P08047
Gene Symbols
SP1
Immunogen
Recombinant fragment corresponding to a region within amino acids 18 and 303 of Human SP1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: 293T, K562, THP-1, HL-60, Raji
- Predicted reactivity: Mouse (96%), Rat (99%), Rhesus Monkey (99%), Bovine (98%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- SP1 is a transcription factor that can activate or repress transcription in response to physiological and pathological stimuli
- Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses
- Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation)
- Binds also the PDGFR-alpha G-box promoter
- May have a role in modulating the cellular response to DNA damage
- Implicated in chromatin remodeling
- Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter
- Plays an essential role in the regulation of FE65 gene expression.