MSH3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA529829-Each-of-1 | In Stock | ₹ 49,083.50 |
PIPA529829 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,083.50
GST (18%): ₹ 8,835.03
Total Price: ₹ 57,918.53
Antigen
MSH3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MSH3
Gene Alias
D13Em1; Divergent upstream protein; DNA mismatch repair protein Msh3; DUC1; DUG; DUP; hMSH3; Mismatch repair protein 1; MRP1; MSH3; mutS homolog 3; mutS homolog 3 (E. coli); protein repair-1; Protein repair-3; REP-1; Rep3; Rep-3
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
4437
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1.79 mg/mL
Formulation
PBS with 20% glycerol and 0.025% ProClin 300, pH 7
Gene Accession No.
P20585
Gene Symbols
MSH3
Immunogen
Recombinant protein fragment corresponding to a region within amino acids 916 and 1137 of Human MSH3
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: A549, H1299
- Predicted reactivity: Human (99%), Mouse (83%), Rat (85%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Component of the post-replicative DNA mismatch repair system (MMR)
- Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair
- When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs
- MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long
- After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.