SP110 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA530070-Each-of-1 | In Stock | ₹ 45,968.50 |
PIPA530070 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,968.50
GST (18%): ₹ 8,274.33
Total Price: ₹ 54,242.83
Antigen
SP110
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SP110
Gene Alias
5031415C07Rik; 52kDa; 5830484A20Rik; ENSMUSG00000075603; IFI41; Ifi75; interferon-induced protein 41, 30kD; interferon-induced protein 41/75; interferon-induced protein 75, 52kD; intracellular pathogen resistance 1; intracellular pathogen resistance protein 1; Ipr1; phosphoprotein 41; phosphoprotein 75; SP110; Sp110 nuclear body protein; speckled 110 kDa; Transcriptional coactivator Sp110; VODI
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3431
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Concentration
0.82 mg/mL
Formulation
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q9HB58
Gene Symbols
SP110
Immunogen
Recombinant protein fragment corresponding to a region within amino acids 1 and 186 of Human SP110
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: 293T, A431, Raji
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Susceptibility to tuberculosis (TB) in mice has recently been attributed to the IPR1 gene
- IPR1 is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component
- The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator
- Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified
- SP110 is the closest homolog of the IPR1 protein in humans
- The IPR1/Sp110 gene product might play a role in integrating signals generated by intracellular pathogens with mechanisms controlling innate immunity, cell death, and pathogenesis
- IPR1/Sp110 is up-regulated after infection with M
- tuberculosis and required by Anaplasma phagocytophilum for infection of human promyelocytic cells
- Defects in Sp110 are a cause of severely impaired resistance to infection by M
- tuberculosis.