TOX Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA530328-Each-of-1 | In Stock | ₹ 49,439.50 |
PIPA530328 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,439.50
GST (18%): ₹ 8,899.11
Total Price: ₹ 58,338.61
Antigen
TOX
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TOX
Gene Alias
1700007F02Rik; KIAA0808; thymocyte selection associated high mobility group box; thymocyte selection-associated high mobility group box; thymocyte selection-associated high mobility group box protein TOX; thymocyte selection-associated HMG box; thymus high mobility group box protein TOX; TOX; TOX1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
252838, 9760
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.4 mg/mL
Formulation
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.
O94900, Q66JW3
Gene Symbols
TOX
Immunogen
Recombinant fragment corresponding to a region within amino acids 55 and 301 of Human TOX
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: THP-1, HL-60
- Predicted reactivity: Mouse (89%), Rat (91%), Rhesus Monkey (99%), Bovine (94%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- TOX (thymocyte selection-associated high mobility group (HMG) box protein) is a member of the HMG box family of DNA-binding proteins and likely plays a role in the regulation of T-cell development
- It is a 526 amino acid nuclear protein and the expression of TOX is upregulated by pre-T cell receptor (pre-TCR) and TCR activation in immature thymocytes
- TOX-mediated positive selection is associated with up-regulation of RUNX3 and is calcineurin dependent
- TOX-dependent transition to the CD4+CD8 stage is required for development of class II major histocompatibility complex-specific T cells.