DCUN1D1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA530744-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA530744 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
DCUN1D1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
DCUN1D1
Gene Alias
DCN1; DCN1, defective in cullin neddylation 1, domain containing 1; DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae); DCN1-like protein 1; DCNL1; DCUN1 domain-containing protein 1; Dcun1d1; DCUN1L1; defective in cullin neddylation 1 domain containing 1; defective in cullin neddylation protein 1-like protein 1; pTes3; Rp42; RP42 homolog; SCCRO; SCRO; squamous cell carcinoma related oncogene; squamous cell carcinoma-related oncogene; Tes3; testis derived transcript 3; testis-specific protein 3
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
54165
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Concentration
0.3 mg/mL
Formulation
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q96GG9
Gene Symbols
DCUN1D1
Immunogen
Recombinant fragment corresponding to a region within amino acids 58 and 259 of Human DCUN1D1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: 293T, A431, Jurkat, Raji
- Predicted reactivity: Mouse (99%), Zebrafish (92%), Xenopus laevis (99%), Chicken (99%), Rhesus Monkey (100%), Bovine (100%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Part of an E3 ubiquitin ligase complex for neddylation
- Promotes neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes
- Acts by binding to cullin-RBX1 complexes in the cytoplasm and promoting their nuclear translocation, enhancing recruitment of E2-NEDD8 (UBE2M-NEDD8) thioester to the complex, and optimizing the orientation of proteins in the complex to allow efficient transfer of NEDD8 from the E2 to the cullin substrates
- Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity (PubMed:25349211, PubMed:28581483)
- Acts also as an oncogene facilitating malignant transformation and carcinogenic progression
- [UniProt]