PIPA530883

Munc13-4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA530883-Each-of-1 In Stock ₹ 46,502.50

PIPA530883 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

Munc13-4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Unc13d

Gene Alias

2610108D09Rik; FHL3; HLH3; HPLH3; Jinx; likely ortholog of H. sapiens unc-13 homolog D (UNC13D); mFLJ00067; munc 13-4; Munc13-4; Protein unc-13 homolog D; unc-13 homolog D; unc-13 homolog D (C. elegans); Unc13d

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

201294, 70450

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

B2RUP2, Q70J99

Gene Symbols

Unc13d

Immunogen

Recombinant fragment corresponding to a region within amino acids 8 and 222 of Human Munc 13-4

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: A431, mouse lung
  • Predicted reactivity: Mouse (87%), Rat (91%), Bovine (86%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins
  • The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion
  • Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.