LIN7B Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA531018-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA531018 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
LIN7B
Classification
Polyclonal
Conjugate
Unconjugated
Gene
LIN7B
Gene Alias
hLin7B; hVeli2; lin 7 homolog b; lin-7 homolog B; lin-7 homolog B (C. elegans); lin-7 homolog B, crumbs cell polarity complex component; lin-7-A; LIN7B; lin-7B; MALS2; MALS-2; Mammalian lin-seven protein 2; protein lin-7 homolog B; UNQ3116/PRO10200; Veli1a; Veli2; Veli-2; veli-2 protein; vertebrate homolog of C. elegans Lin-7 type 2; vertebrate lin-7 homolog 2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
64130
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Concentration
0.69 mg/mL
Formulation
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q9HAP6
Gene Symbols
LIN7B
Immunogen
Recombinant fragment corresponding to a region within amino acids 7 and 207 of Human LIN7B
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: 293T, A431
- Predicted reactivity: Mouse (97%), Rat (97%), Zebrafish (92%), Pig (99%), Chicken (86%), Rhesus Monkey (100%), Bovine (100%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells
- Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains
- The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain
- Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin
- Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells
- May increase the amplitude of ACCN3 acid-evoked currents by stabilizing the channel at the cell surface.