CCR2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA533393-Each-of-1 | In Stock | ₹ 49,884.50 |
PIPA533393 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,884.50
GST (18%): ₹ 8,979.21
Total Price: ₹ 58,863.71
Antigen
CCR2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Ccr2
Gene Alias
C-C chemokine receptor type 2; C-C CHEMOKINE RECEPTOR TYPE 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2) (JE/FIC RECEPTOR) (MCP-1 RECEPTOR); C-C CKR-2; C-C motif chemokine receptor 2; Cc-ckr2; CC-CKR-2; Ccr2; CCR-2; Ccr2a; CCR2B; CD192; CD192 antigen; chemoattractant protein-1 receptor; chemokine (C-C motif) receptor 2; chemokine (C-C) receptor 2; chemokine receptor CCR2; Ckr2; Ckr2a; Ckr2b; CMKBR2; hCG_14621; JE/FIC receptor; Mcp1 receptor; MCP-1 receptor; Mcp1r; MCP-1-R; MIP-1 alphaR; mJe-r; Monocyte chemoattractant protein 1 receptor; monocyte chemotactic protein 1 receptor
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
729230
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin)
Concentration
1 mg/mL
Formulation
PBS with 0.1% sodium azide
Gene Accession No.
P41597
Gene Symbols
Ccr2
Immunogen
Synthetic 20 amino acid peptide from 2nd extracellular domain of human CCR2.
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Percent identity with other species by BLAST analysis: Human, Gorilla (100%) Gibbon (95%) Monkey (90%)
- CCR2, a chemokine receptor, is a regulator of monocyte/macrophage traffickings and is upregulated in response to inflammation
- Resistance to HIV-1 infection or delayed progression to AIDS may be linked to CCR2 polymorphisms
- The ligand for CCR2 is monocyte chemoattractant protein (MCP-1), a chemokine produced by endothelial cells, smooth muscle cells, and macrophages
- Activation of monocytes by MCP-1 may mediate the monocytic infiltration of tissues in atherosclerosis and other inflammatory disorders including rheumatoid arthritis, alveolitis, and tumor infiltration
- Two isoforms are produced by alternative splicing
- CCR2 has been reported to be expressed in a wide variety of tissues, including blood, brain, heart, kidney, liver, lung, ovary, pancreas, spinal cord, spleen, thymus, and vessel
- Increased expression of CCR2 has been documented in CD3+ lymphocytes in rheumatoid arthritis
- ESTs have been isolated from liver/spleen and prostate libraries.