PIPA533905

LPHN2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA533905-Each-of-1 In Stock ₹ 46,502.50

PIPA533905 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

LPHN2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ADGRL2

Gene Alias

Adgrl2; Adhesion G protein-coupled receptor L2; AI450192; Calcium-independent alpha-latrotoxin receptor 2; calcium-independent alpha-latrotoxin receptor homolog 2; Cirl2; Cirl-2; Cl2; Cl2aa; Cl2ac; Gm619; KIAA0786; latrophilin 1; latrophilin 2; latrophilin homolog 1; Latrophilin-2; LEC1; Lectomedin-1; LPHH1; Lphn2; mKIAA0786

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

23266

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

1 mg/mL

Formulation

PBS with 0.1% sodium azide

Gene Accession No.

O95490

Gene Symbols

ADGRL2

Immunogen

Synthetic 16 amino acid peptide from N-terminal extracellular domain of human LPHN2.

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey (100%) Gorilla, Marmoset, Mouse (94%) Rat, Dog, Panda (88%)
  • The Latrophilin family of G protein-coupled receptors consists of three members, latrophilin-1, 2 and 3, each of which displays distinct tissue distribution and function
  • Latrophilin-1, the most characterized member of this family, acts as a receptor for a-latrotoxin, a component of venom from the black widow spider
  • Binding of a-latrotoxin to latrophilin-1 triggers synaptic vesicle exocytosis via both Ca2+-dependent and -independent mechanisms, resulting in vesicle depletion
  • Latrophilin-1 is abundant in brain and present in endocrine cells
  • Latrophilin-3 is also brain-specific, whereas latrophilin-2 expression is ubiquitous.