PIPA533916

MLK1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA533916-Each-of-1 In Stock ₹ 46,502.50

PIPA533916 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

MLK1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MAP3K9

Gene Alias

E130314H24Rik; Map3k9; MEKK9; mitogen activated protein kinase kinase kinase 9; mitogen-activated protein kinase kinase kinase 9; Mixed lineage kinase 1; mixed lineage kinase 1 (tyr and ser/thr specificity); mixed-lineage kinase 1; MLK1; Prke1; RGD1562149

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100054289, 100341731, 338372, 4293

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

1 mg/mL

Formulation

PBS with 0.1% sodium azide

Gene Accession No.

P80192, Q3U1V8

Gene Symbols

MAP3K9

Immunogen

Synthetic 18 amino acid peptide from internal region of human MAP3K9.

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Equine, Human, Mouse, Non-human Primate, Rabbit

Product Type

Antibody

Isotype

IgG

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Description

  • Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Panda, Dog, Horse, Rabbit (100%) Hamster, Elephant, Bovine, Bat, Pig (94%)
  • MAP3K9 (MLK1) is a serine/threonine protein kinase that functions in the MAP kinase pathway
  • Plays an important role in the cascades of cellular responses evoked by changes in the environment
  • Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade through the phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7 which in turn activate the JNKs
  • The MKK/JNK signaling pathway regulates stress response via activator protein-1 (JUN) and GATA4 transcription factors
  • Plays also a role in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis.